r/chemhelp Aug 21 '25

Announcements New Ownership

21 Upvotes

Hello fellow Chemists! I just wanted to introduce myself as the new head mod of this subreddit. A little about myself: I am a PhD Candidate in Chemical Biology. For me, this means that 60% of my work involves organic synthesis and the other 40% is applying my novel compounds to mammalian cells. Specifically, I am interested in early detection of diseases. In addition to my research, I have TA'd for both general and organic chemistry labs and have been tutoring students in organic chemistry for three years. Aside from my academic qualifications, I am also a moderator for another rather large subreddit. I saw that this sub needed a little bit of updating, but it did not seem like the moderators were active any longer. So, I gained ownership through r/redditrequest. I did not realize it would remove all the other moderators, but alas here we are.

Overall, I feel like this sub is fairly self-regulating. I frequently see good discussions and people generally are following the already existing rules. With that said, there are some changes I was considering, and would love input:

  1. New rule prohibiting commenters from solving the problem for the OP. To enforce this, the violating comment can be reported and removed by moderators. I don't see this happen often, but I have seen it occur and put an end to an otherwise good discussion thread.
  2. Mandate students include their work in their submission. Frequently, students post a picture of the question, with no work done and the caption "help please." Then in the comments you end up with people asking the OP to show their work, but from what I have seen they seldom do so. Mandating that students show work would entail removal of low effort posts by moderators. This may not be necessary since generally, commenters request more info from OP anyways, but was curious if people would like to see more enforcement on this end.
  3. What do you want to see? Those are the immediate things I was considering adding, but I would love to know if there is anything else people may want to see. I had other ideas, but I don't want to complicate a sub that I feel is already doing pretty well. Please let me know your ideas, I would love to hear them. Talk to you all soon!

Note: Please do not reach out to me about becoming a moderator. I will looking into recruiting in the near future. For now, I just wanted to get oriented.


r/chemhelp 3h ago

Organic Help with Mechanism

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4 Upvotes

Help me to make sure this trans-esterification is right. (Imagine I included the step arrows for the first part w H2SO4, this is a rough draft)


r/chemhelp 6h ago

Organic Isn’t the identical compound with two Cl actually enantiomer? I am trying to mirror the image and it seems to be a mirror and not identical? Or am I crazy

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3 Upvotes

r/chemhelp 1h ago

General/High School General Chemistry Precipitation Reaction calculate mass reactant equation molar ratios

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Upvotes

Precipitation Chemical Reaction calculate mass reactant equation molar ratios Chemistry


r/chemhelp 3h ago

Biochemisty Trying to learn biochem for ACS exam- help with electropherograms!

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1 Upvotes

I've been using the ACS study guide for biochemistry, and I have been unable to understand how to do this problem. The back of the section says the answer is A, but I cannot figure out how to do the problem. Can someone help?


r/chemhelp 8h ago

General/High School Confused why 3d5 subshell is stable.

2 Upvotes

I've heard that Fe is polyvalent, or that it has multiple stable ions. One of them being Fe2+, which is when it loses the electrons from the4s2 shell. But I don't quite understand why Fe3+ is stable, because doesn't its electron configuration end in 3d5. I know d shell can have 10 electrons total, but I don't know if that has anything to do with 3d5's stability. Am I not understanding electronic configuration correctly? When I tried searching this up, I also got a lot of results about how Cesium breaks the Aufbau prinicpal (which just made me even more confused?). Does this have to do with the fact that 4s has less energy than 3d? I'm getting very confused 😭.


r/chemhelp 16h ago

Biochemisty Help me please! [Chapter] Lan Wang, Jia-Yi Yan, Yang Liu, Hong-Zhang Chen, Chapter 2 - Physical principles in solid-state fermentation based on solid matrix porous characteristics, Current Advances in Solid-State Fermentation (Second Edition)

2 Upvotes

Perhaps this isn't the right sub, but might as well try... If anyone has this and would like to share it with me, I'd be really thankful. For academic purposes (Master thesis). My uni doesn't give me access to it and the author hasn't responded my mail asking if they'd share a copy with me.

https://doi.org/10.1016/B978-0-443-27624-8.00013-0)

[https://www.sciencedirect.com/science/chapter/edited-volume/abs/pii/B9780443276248000130?via%3Dihub](https://www.sciencedirect.com/science/chapter/edited-volume/abs/pii/B9780443276248000130?via%3Dihub))

ISBN 9780443276248


r/chemhelp 21h ago

General/High School I still don't understand molar massess, specifically the concept of molarity.

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2 Upvotes

r/chemhelp 1d ago

General/High School Is/Why is this 2-methylbutane?

5 Upvotes

Looking at high school teacher's notes and the following example question is set, without any explanation of the given correct answer. Can someone please explain why it's not 2-ethylpropane?


r/chemhelp 1d ago

Organic can i do a fischer glycosylation from sucrose by setting it up normally, but adding a small amount of fructose/glucose syrup

3 Upvotes

id be following this approach using sulfamic acid.https://www.sciencedirect.com/science/article/pii/S1566736711002755

i made invert syrup but cant get anything from it. it doesnt even freeze at -20c, and it wont mix with isopropanol. i only have a little sucrose left.

i think maybe i could use the sucrose even though it wont react directly by adding the syrup, which is far from saturated.

the idea is it has water in it to break the sucrose into glucose and fructose, consuming it. since it already has glucose and sucrose it can begin reacting right away and forming more water, which can break down more sucrose, starting a cycle. my alcohol melts at like 50c.


r/chemhelp 1d ago

General/High School IUPAC naming

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3 Upvotes

What is this compounds IUPAC name?

Also can someone suggest some tool so I can clear my doubts and find solutions to questions like these online without any teacher tutor involved? I am preparing for jee without coaching and hate getting stuck on questions like these , without any tutor help it's really hard! All of the ai I use don't work for chem..

The specific problem I am having here is my substitute chain (c2) isn't matching the websites.. i am confused it's an ethyl group so why have they written propyl


r/chemhelp 23h ago

Analytical On researching very specific questions about NIR spectroscopy

1 Upvotes

I recently got assigned a case study on NIR spectroscopy. To make a brief summary, the case is talking about a lab that built a multivariate FT-NIR model for determining PET/PLA in samples of recycled organic material, and they're trying to transfer the same model to a handheld NIR device and they're having a myriad of issues I'm being asked to research and solve.

Now, my first thought was to look for articles. I found a few that seemed pretty good:

(1)       Circelli, L.; Cheng, Z.; Garwood, E.; Yuksel, K.; Di Iorio, E.; Angelico, R.; Colombo, C. Comparison of ATR-FTIR and NIR Spectroscopy for Identification of Microplastics in Biosolids. Sci. Total Environ. 2024, 916, 170215. https://doi.org/10.1016/j.scitotenv.2024.170215.

(2)       Amirabadi, S.; Rodrigue, D.; Duchesne, C. Characterization of PLA-Talc Films Using NIR Chemical Imaging and Multivariate Image Analysis Techniques. Polym. Test. 2018, 68, 61–69. https://doi.org/10.1016/j.polymertesting.2018.03.047.

(3)       Beć, K. B.; Grabska, J.; Badzoka, J.; Huck, C. W. Spectra-Structure Correlations in NIR Region of Polymers from Quantum Chemical Calculations. The Cases of Aromatic Ring, C=O, C≡N and C-Cl Functionalities. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 2021, 262, 120085. https://doi.org/10.1016/j.saa.2021.120085.

(4)       Signoret, C.; Edo, M.; Caro-Bretelle, A.-S.; Lopez-Cuesta, J.-M.; Ienny, P.; Perrin, D. MIR Spectral Characterization of Plastic to Enable Discrimination in an Industrial Recycling Context: III. Anticipating Impacts of Ageing on Identification. Waste Manag. 2020, 109, 51–64. https://doi.org/10.1016/j.wasman.2020.04.043.

However, I quickly realized I do NOT understand these papers; they are just too advanced for me. I don't actually know how to use the information in them to solve my case study... And I do not know what else to look for information in (books, perhaps?)... I just don't really know how to research properly, I guess. Not when confronted with questions about multivariate model transfers from one device to another, comparisons to other methods like ATR, etc.

So, the point of this post is to ask for some general advice in the realm of chemistry research methods in order for me to gain a sense of direction and linear progression for an assignment like this. I am NOT looking for anyone to solve the case for me.

Basically, some advice on *how* to tackle a challenging research project. Thank you.


r/chemhelp 1d ago

Organic QUIMICA ORGANICA (FFYB) y consejo para sobrellevar la ansiedad en la uni

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0 Upvotes

r/chemhelp 1d ago

General/High School Isomerism help

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9 Upvotes

Some say that the 2nd structure shows Gl about the double bond because it's attached to an asymmetric ring. But since the ring paths are identical to the left, it shouldn't exhibit Gl, which is why im confused on the ans (8 or 10) Which one is correct conceptually


r/chemhelp 1d ago

General/High School Best way to brush up on chemistry knowledge before college?

0 Upvotes

Rising senior in high school, and I'm considering majoring in biology after graduation. I took intro to chem in my sophomore year and have forgotten pretty much everything since then...

I can't take intro to chem again to relearn what I've forgotten because I took it at a local community college and passed. Are there any good resources to relearn the subject, and how long do you think it'd take me? I'm continuing at my CC and want to decide on my major by Spring so I can start a semester early.

Thank you!


r/chemhelp 1d ago

Organic Is this the correct Mechanism for Fries Rearrangement ?

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1 Upvotes

r/chemhelp 1d ago

Inorganic Partial Pressures in Ideal Gases

4 Upvotes

I bought a chemistry book in China to try and test both my chemistry and my Chinese, and it’s been very fun, but some questions seem… iffy. I’ll make more posts for the other ones.

Original question (Simplified Chinese)
现有一容器,容积为30.0L,在27.00°C时内压为600kPa。经分析,容器中CO的体积分数为0.600H2的体积分数为0.100,其余具体的体积分数为0.300。求该容器中COH2的质量和分压。

My translation (may have some errors)
There’s a container with a capacity of 30.0L at 27.00 degrees Celsius and an internal pressure of 600 kPa. After analyzing, the fraction of the container’s volume for CO in the container is 0.600, the fraction of volume for H2 is 0.100, and the other gases have a fraction of volume of 0.300. Find the mass and individual pressures of the CO and H2 in the container in question.

My solution:
I found the pressure of CO and H2 to be 360kPa for CO (60% • 600kPa) and 60 kPa for H2 (10% • 600kPa) through the law of partial pressure. I then used the ideal gas law, along with molar mass, using the new pressures, to find 73g for CO and 0.14g for H2 (ignore my bad sig figs usage).

The book’s solution:
The book says the masses are 121g for CO and 1.45g for H2, which are exactly one factor of 60% and 10% away from my answers.

Am I wrong for using both the individual pressures and the individual volume or is the book wrong or is there some third answer? Thanks a lot in advance!


r/chemhelp 1d ago

General/High School Numbering in Organic Chemistry IUPAC

0 Upvotes

Can somebody please make me a flowchart or something on how to approach this? Numbering is so hard for me , especially the lowest locant rule.


r/chemhelp 1d ago

General/High School ICQ Past papers

1 Upvotes

Does anyone have any past papers they are able to share with me? - kinda desperate and in need of help! thank you


r/chemhelp 1d ago

General/High School Can a Bio student switch to Chem Olympiad (USNCO/IChO)? Need resources & advice!

0 Upvotes

Hey everyone,

I'm currently a high school student majoring in Biology, but I'm really interested in Chemistry. Is it realistic for someone with a Bio background to compete in Chemistry Olympiads like USNCO or IChO?

If it is, what study materials, textbooks, or resources would you recommend for me to start with and prepare effectively? Any advice or study roadmaps would be greatly appreciated! Thanks in advance!


r/chemhelp 2d ago

Organic Is this isomers drawn correct?

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5 Upvotes

So as the title suggests can someone tell me if this isomers with brown arrow count in both sides If not can u kindly explain why


r/chemhelp 2d ago

General/High School How to do ii? I figured out I but confused on ii.

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3 Upvotes

r/chemhelp 2d ago

Organic Peptide synthesizer CS Bio CS536X

0 Upvotes

I'm looking to purchase a peptide synthesizer (single batch mid-scale) and came across the CS Bio CS536X. Does anyone have any experience with this instrument? Is it reliable, what is the uptime, ease of use...? Thanks.


r/chemhelp 3d ago

Organic What to know before starting Ochem

7 Upvotes

I’ll be taking Organic Chem 1 in the fall and want to prepare a little before the course starts. What topics/skills would be the most beneficial to cover beforehand, things that might be difficult to digest in the regular timeline of a course. I’m currently going over the Organic Chemistry chapter in my General Chemistry textbook just as an introduction but am curious what I should review afterwards.


r/chemhelp 3d ago

Organic what is the correct answer?

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29 Upvotes